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Contraindicated (1)pentobarbital will minimize the extent or influence of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is liable for the formation and elimination of cariprazine's Lively metabolites.Also fast administration might cause respiratory despair, laryngospasm, apnea, or vasodilation with drop in blood pressure
pentobarbital will reduce the extent or effect of aprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will reduce the level or influence of fentanyl transmucosal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead to your lessen in fentanyl plasma concentrations, not enough efficacy or, maybe, development of the withdrawal syndrome inside of a affected individual that has produced physical dependence to fentanyl.
pentobarbital will decrease the extent or impact of meloxicam by influencing hepatic enzyme CYP2C9/10 metabolism. Insignificant/Significance Not known.
pentobarbital will lower the extent or effect of vardenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Check Intently (1)pentobarbital will decrease the level or outcome of mifepristone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. CYP3A4 inducers haven't been examined, coadministration not recommended by producer
pentobarbital will lower the extent or effect of lorlatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or result of cilostazol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will reduce the level or outcome of bosentan by influencing hepatic enzyme CYP2C9/ten metabolism. Insignificant/Significance Unidentified.
pentobarbital will minimize the extent or effect of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Influence of coadministering a solid CYP3A4 inducer with fedratinib hasn't been examined.
pentobarbital will minimize the level or influence of budesonide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
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Status epilepticus: Pentobarbital is usually administered in refractory standing epilepticus based on more info the AAN guidelines for convulsive position epileptics.